1.
Color Configuration in Adobe Captivate lets you tailor the look and feel of the Captivate interface itself, giving you control over its visual environment.
System Colors, on the other hand, are tied to the color scheme of the project you’re working on, ensuring a consistent look across all elements.

2.
Color Configuration is primarily used to adjust the appearance of the Captivate workspace, enhancing your working experience.
System Colors help maintain a cohesive and unified color palette throughout your project, ensuring consistency across all slides.

3.
Color Configuration can be customized based on your preferences.
With System Colors, any change you make to a color will automatically update all project elements using that color, streamlining the design process.