Purchase Aspadol Online with bulk Discounts Aspadol is a prescription medication containing tapentadol, a synthetic analgesic used to treat moderate to severe pain. Available in various strengths, including 50mg, 100mg, and 200mg, Aspadol works by binding to opioid receptors in the brain and increasing the levels of norepinephrine, which helps reduce pain signals. It is commonly prescribed for conditions such as chronic back pain, osteoarthritis, and post-surgical pain.